Package index • cTOST

Average Equivalence Testing

Functions for testing equivalence of means in univariate and multivariate settings using finite sample corrections (alpha-TOST, delta-TOST, optimal cTOST).

ctost(): Finite Sample Adjustment for Average (Bio)Equivalence Assessment

compare_to_tost(): Comparison of a Corrective Procedure to the results of the Two One-Sided Tests (TOST) in Univariate Settings

Quantile Equivalence Testing

Functions for testing equivalence at specific quantiles or across multiple quantiles.

qtost(): Quantile equivalence testing procedures

compare_to_qtost(): Comparison of a Corrective Procedure to the Results of the Quantile Two One-Sided Tests (qTOST) in Single Quantile Setting

Differential Privacy Equivalence Testing

Functions for equivalence testing under differential privacy constraints.

prop_test_equiv_dp(): Differentially Private TOST for Proportion Equivalence Testing

tost_equiv_dp(): Differentially Private TOST for Mean Equivalence Testing

Visualization and Output

Print and plot methods for displaying test results.

plot(<tost>): Plot confidence intervals for one or more `tost` or `mtost` objects

print(<tost>): Print Results of (Bio)Equivalence Assessment in Univariate Settings

print(<mtost>): Print Results of (Bio)Equivalence Assessment in Multivariate Settings

print(<qtost>): Print Results of (Bio)Equivalence testing in Single Quantile Setting.

print(<m_qtost>): Print Results of (Bio)Equivalence testing in Two Quantiles Setting.

print(<prop_test_dp>): Print Results of DP-TOST for Proportions

print(<tost_dp>): Print method for DP-TOST mean test

Datasets

Real datasets for bioequivalence studies and examples.

skin: Log transformed cutaneous delivery of econazole (ECZ) from bioequivalent products on porcine skin

ticlopidine: Ticlopidine Bioequivalence Data

skin_mvt: Multivariate Skin Bioequivalence Data

biodistribution: Biodistribution Data

Internal/C++ Functions

Low-level C++ implementations for differential privacy computations.

tost_dp_one_sample_ultra_fast(): Ultra-fast C++ DP-TOST using Nelder-Mead (100x target)